ABSTRACT
The presence of a non-resolving pneumonia warrants the suspicion of a possible malignancy. While pulmonary involvement in Hodgkin’s disease can present as a non-resolving pneumonia, the clinical clues of dyspnoea, stridor and wheeze point to a possible endobronchial involvement. A bronchoscopy in such a situation can be valuable for diagnosis, and can aid in staging of the disease. The true incidence of endobronchial involvement in Hodgkin’s disease is not known, but when diagnosed early and treated appropriately, the prognosis is usually good, and a complete cure is possible.
Subject(s)
Biopsy , Bronchial Neoplasms/complications , Bronchial Neoplasms/diagnosis , Bronchoscopy , Child , Diagnosis, Differential , Female , Hodgkin Disease/complications , Hodgkin Disease/diagnosis , Humans , Pneumonia/diagnosis , Pneumonia/etiology , Tomography, X-Ray ComputedABSTRACT
A 40-year-old male presented with clinical and radiological manifestations of right lung atelectasis and post-obstructive pneumonia. Flexible bronchoscopy revealed gross narrowing of the right upper lobe bronchus and a smooth, white endobronchial mass completely occluding the right lower lobe bronchus. Endobronchial biopsy from the mass lesion yielded low grade B-cell non-Hodgkin’s lymphoma. This is one of the rarest presentation of non-Hodgkin’s lymphoma.
Subject(s)
Adult , Bronchial Neoplasms/diagnosis , Bronchial Neoplasms/drug therapy , Bronchial Neoplasms/diagnostic imaging , Bronchoscopy , Humans , Lymphoma, Non-Hodgkin/diagnosis , Lymphoma, Non-Hodgkin/drug therapy , Lymphoma, Non-Hodgkin/diagnostic imaging , Male , Tomography, X-Ray ComputedABSTRACT
The endobronchial presentation of Hodgkin's disease is defined as : 1) having the histological features of Hodgkin's disease, irrespective of the biopsy site, and 2) a bronchoscopic visualization of an endobronchial tumor at the time of the initial diagnosis1. The presentation of Hodgkin's disease, as an endobronchial lesion, is very uncommon, with only a few isolated cases having been reported, and no accurate incidence is available. An endobronchial lymphoma must be considered when patients present with an endobronchial tumor, as careful staging and treatment may lead to a cure and avoid of the need for major surgery. Also, when patients, with a known lymphoma, present with respiratory symptoms, they should be considered for a bronchoscopy to avoid understaging of the disease. Herein, a case of endobronchial Hodgkin's disease, in a 20-year-old woman, is reported.